House Party Material

Hey guys, I got a question for ya, not sure if you approach it differently or not but ill go ahead and ask anyway. So is there any difference between the tactics one would use at a social gathering like a house party (ie most people know each other) vs a bar in say uptown? Reason I ask is I'm hitting up 2 house parties this weekend, both costume parties. I just wanted to see what kind of material, mainly what sort of openers y'all think would work well in a small environment of people?
Thanks for the input guys!
-Suit
Thanks for the input guys!
-Suit